Endocrine Abstracts

Kisspeptin is an undisputed regulator of sexual maturation and reproductive function across mammalian species. Mutations in human patients in either kisspeptin and/or its receptor are rare in number but prismatic in scope and have led to unique genotype/phenotype and structure/function correlations. Mice with targeted deletions of either kisspeptin or its receptor have also contributed greatly to our understanding of the physiology underlying this critical pathway in reproduct...